Updated April 5, 2026 — Prices updated regularly from EIA data
Route • 1 states
About Interstate 376
Running 43 miles through Pittsburgh, PA, I-376 serves the Pittsburgh metro area. As with all Pennsylvania interstates, the state's high fuel tax affects prices along this route.
Interstate 376 spans 1000 miles across multiple states. For a vehicle averaging 28 MPG highway, the fuel cost varies significantly depending on which states and price zones the route covers.
Interstate 376 passes through or near major cities where competitive fuel markets and warehouse clubs offer the best prices. Look for Costco, Sam's Club, or high-volume discount stations in each major metro along your route.
A 2-mile detour to save 20 cents per gallon on a 15-gallon fill-up saves $3. With a car getting 28 MPG, the detour uses 0.14 gallons. Detours above 3-4 miles for savings under 20 cents per gallon are generally not worthwhile.
The cheapest gas along Interstate 376 is generally found in Pennsylvania, where lower fuel taxes and proximity to refineries or pipelines keep prices down. Avoid fueling at highway-exit stations in Pennsylvania, where tourist premiums push prices 15-25 cents above the best nearby rates.
For a trip along Interstate 376, a vehicle averaging 25 MPG would use approximately 1 gallon per 25 miles. At current average prices along the route, budget approximately {perMileCost} cents per mile for fuel. Plan fill-ups in lower-price states whenever possible.