Updated April 5, 2026 — Prices updated regularly from EIA data
Route • 4 states
About Interstate 65
Running 887 miles from Mobile, AL to Gary, IN, I-65 is the primary north-south corridor through the Gulf South and Midwest. Alabama and Tennessee sections offer very affordable fuel, while Indiana prices trend moderate.
Yes — consistently. Highway-exit gas stations charge 10-25 cents more per gallon than stations just 1-2 miles off the interstate. Whenever possible, exit the highway and drive to a commercial area for competitively priced fuel.
Gas prices along Interstate 65 vary significantly by state due to different fuel tax rates. States like Texas (20 cents/gallon), Missouri (17 cents), and Oklahoma (20 cents) consistently offer the most affordable fuel. Pennsylvania (59 cents) and California (67 cents) are among the most expensive.
Fill your tank before entering high-price states along your Interstate 65 route. Use the GasBuddy app to see upcoming prices and plan fill-up stops at the cheapest available locations. Always fill up when you have a quarter tank remaining — running low limits your options.
Interstate 65 passes through several states on its route. Oil-producing states like Texas, Oklahoma, Louisiana, North Dakota, and Wyoming typically offer the cheapest gas along any interstate that traverses them.
The average gas price along Interstate 65's route today blends prices from all the states the highway passes through. This blended average reflects both high-price and low-price state markets along the full corridor.